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Research Findings Resulting from OHS Data

Effect of Cognitive Reserve on the Association of Vascular Brain Injury With Cognition: Analysis of the PURE and CAHHM Studies

Feb 15, 2022

Researchers at the Population Health Research Institute (PHRI) performed a cross-sectional analysis of two harmonized studies: the Canadian Alliance for Healthy Hearts and Healthy Minds (CAHHM), which includes a subset of OHS and CanPath participants, and the Prospective Urban and Rural Epidemiology (PURE) study. The analysis concluded that to improve cognitive brain health, prevention of cerebrovascular disease and the promotion of positive lifestyles are needed.

Read the full article in the journal Neurology

Read the abstract on PubMed

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Psychosocial factors and cancer incidence (PSY-CA): Protocol for individual participant data meta-analyses

Oct 15, 2021

Harmonized psychosocial and cancer questionnaire data from 18 cohorts, including those from the Ontario Health Study and fellow CanPath cohorts CARTaGENE and Atlantic PATH, will be analyzed to clarify the relationship between cancer risk and psychosocial factors (including depression, anxiety, and relationship status).

Read the article at the Wiley Online Library

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Examining the etiology of early-onset breast cancer in the Canadian Partnership for Tomorrow’s Health (CanPath)

Oct 15, 2021

The incidence of breast cancer in women under age 50 is rising, yet the cause of this remains unknown. Approved in early 2020, a matched case-control study using data from 3 cohorts of the Canadian Partnership for Tomorrow’s Health (CanPath), the Ontario Health Study, the BC Generations Project, and Alberta’s Tomorrow Project was published in the journal Cancer Causes & Control, concluding that measures of adiposity, pregnancy history, and family history of breast cancer are important risk factors for early-onset breast cancer.

Read the abstract here

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